For Menopause Symptoms and Dysautonomia
There are a number of clinical studies reported that γ-oryzanol is beneficial in the treatment of relieving menopausal (climacteric) symptoms. Meanwhile, there is a study that γ-oryzanol improved the condition of post traumatic dysautonomia from head injuries and no side effects reported at large dosage.
The effect of γ-oryzanol on menopausal symptoms and dysautonomia
| Application | Dose (mg/d) | Duration (day) | Effect |
|---|---|---|---|
| Menopausal symptoms | 5-10 | 10-38 days | >50% reduction of menopausal index |
| 90 | 14 days | 76.6% improvement in symptoms | |
| 15-30 | 7-14 days | 70-90% improvement in dysautonomia | |
| 300 | 4-8 weeks | 80% elevation of symptoms & reduce serum lipid peroxide | |
| Dysautonomia | 135 | 21 | 74% effectiveness |
The effect of γ-oryzanol on the duration of illness of dysautonomia
≪Method≫
- Subjects: 31dysautonomia patients (12males 19women)
- Age: 14-52 years old (Ave.35)
- Dosage: 3 times per day, total 45mg γ-oryzanol per day
- Duration: 21days
≪Result≫
74% of sysautonomia was improved.
| Dysautonomia | |||
|---|---|---|---|
| Duration of illness (years) | Number of cases | Effectiveness | Ineffectiveness |
| 0-1 | 12 | 7 (22.6%) | 5 (16.1%) |
| 1-4 | 14 | 11 (35.5%) | 3 (9.6%) |
| 4-8 | 2 | 2 (6.5%) | 0 (0%) |
| 8-12 | 2 | 2 (6.5%) | 0 (0%) |
| 12-20 | 1 | 1 (3.2%) | 0 (0%) |
| Total | 31 | 23 (74.3%) | 8 (25.7%) |
Sasak M. et al., Rinsho to Kenkyu, 41, 347-351 (1964).
The effect of γ-oryzanol on the Menopausal Symptoms
≪Method≫
- Subjects: 40 females who were suffering from menopausal symptoms
- Age: 38-62 years old
- Dosage: 3 times per day, total 300 mg γ-oryzanol per day
- Duration: 4 to 8 weeks
- Evaluation Items: Kupperman Index, Questionnaire
The incidence of individual nonspecific complaints
All symptoms were dramatically improved by taking Gamma Oryzanol.
Ishihara M., Asia-Oceania J. Obestet, Gynaecol. 10(3), 317-323 (1984).
Summary
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74% of sysautonomia was improved.
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90% of the symptoms of menopause was improved.
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A subjective symptom of a climacteric disturbance was recovered 85%.
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During this study, no side effects have been recognized.
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